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Osteogenesis Imperfecta Treatment in India

Comprehensive surgical and medical management of brittle bone disease in children.

Overview

Osteogenesis imperfecta (OI), commonly known as "brittle bone disease," is a genetic disorder characterized by bones that break easily, often with minimal or no apparent trauma. The condition results from defects in type I collagen, the primary protein building block of bone, leading to abnormal bone formation and reduced bone density. OI encompasses a spectrum of severity ranging from mild forms with few fractures to severe forms causing multiple fractures even before birth. While there is no cure for OI, modern orthopedic management has dramatically improved outcomes, allowing many children with OI to lead active, productive lives with proper treatment and support. Dr. Kumar provides comprehensive care for children with osteogenesis imperfecta, addressing both the frequent fractures and the progressive skeletal deformities that characterize this condition. The disorder is classified into several types (Type I through Type VIII), with Type I being mildest and Type II most severe (often lethal). Common features include multiple fractures throughout childhood, blue sclerae (blue-tinted whites of the eyes), hearing loss, dental abnormalities (dentinogenesis imperfecta), short stature, scoliosis and spinal deformities, and ligamentous laxity leading to joint hypermobility. Treatment requires a multidisciplinary approach combining orthopedic surgery, bisphosphonate medications, physical therapy, and supportive care. Surgical management for OI focuses on stabilizing fractures, correcting deformities, and preventing future fractures through intramedullary rodding procedures. Intramedullary rods are metal implants placed inside the long bones (femur, tibia, humerus) to provide internal support and prevent fractures and progressive bowing deformities. Dr. Kumar uses both telescoping rods (which elongate as the child grows) and fixed rods depending on the child's age and bone characteristics. The Fassier-Duval telescoping rod system is particularly valuable for younger children with growing bones. Rodding procedures are typically performed for recurrent fractures in the same bone, progressive angular deformities, or prophylactically in severely affected children to prevent fractures and improve mobility. Medical management with bisphosphonate medications (such as pamidronate or zoledronic acid given intravenously) has revolutionized OI care over the past two decades. These medications increase bone density, reduce fracture frequency, improve bone pain, and enhance mobility in most children with moderate to severe OI. Treatment typically begins in early childhood and continues through adolescence. Physical and occupational therapy are essential components of comprehensive care, focusing on safe strengthening exercises, mobility training with appropriate assistive devices, and activities of daily living adaptations. Aquatic therapy is particularly beneficial, allowing exercise in a low-impact environment. At Arthoscenter, Dr. Kumar collaborates with pediatricians, geneticists, endocrinologists, and rehabilitation specialists to provide holistic care for children with OI and their families. Our approach emphasizes fracture prevention through environmental modifications, safe handling techniques, and appropriate activity guidelines while promoting maximum independence and participation. Surgical outcomes have been excellent, with intramedullary rodding significantly reducing fracture frequency and improving ambulation in most children. Family education and psychological support are integral to our program, helping parents and children navigate the challenges of living with this lifelong condition while maintaining optimism about achievable functional goals.

Symptoms & Indications

This surgery may be recommended if you experience:

Multiple bone fractures with minimal trauma

Blue or gray-tinted sclerae (whites of eyes)

Short stature for age

Progressive limb deformities (bowing)

Scoliosis or kyphosis (spinal curvature)

Hearing loss (usually develops in adulthood)

Dental problems (brittle teeth)

Joint hypermobility and laxity

Easy bruising

Family history of similar condition

Procedure Details

Duration

2-4 hours per bone

Anesthesia

General Anesthesia

Preparation for Surgery

Comprehensive evaluation including genetic testing, bone density scan, skeletal survey. Bisphosphonate infusion optimization pre-surgery.

Surgical Steps

1

General anesthesia with careful positioning

2

Fracture reduction if acute fracture present

3

Longitudinal incision over affected bone

4

Entry point creation at bone end

5

Intramedullary canal preparation

6

Telescoping or fixed rod insertion

7

Proximal and distal fixation of rod

8

Correction of angular deformities if present

9

Osteotomy (bone cut) for severe deformities

10

Wound closure in layers

11

Cast or splint application

12

Post-op bisphosphonate therapy continuation

Recovery Timeline

What to expect during your recovery journey

Week 1-4

Initial healing

Protected mobilization, pain management, cast care

Week 5-12

Progressive rehabilitation

Gentle range of motion, protected weight bearing

Month 4-6

Strengthening

Supervised therapy, gradual activity increase

Long-term

Lifelong management

Ongoing bisphosphonate therapy, fracture prevention

Tips for Faster Recovery

Bisphosphonate infusions continue per protocol

Gentle handling essential to prevent fractures

Physical therapy crucial for strength and mobility

Aquatic therapy excellent low-impact option

Environmental modifications for safety

Assistive devices as needed (wheelchair, braces)

Nutrition optimization with calcium and vitamin D

Regular bone density monitoring

Fracture frequency typically decreases after rodding

Telescoping rods may need adjustment during growth

Multidisciplinary team follow-up essential

Focus on achievable functional independence

Frequently Asked Questions

Common questions about this procedure

Q1.What is the recovery time?

Initial surgical recovery 3-6 months. OI requires lifelong management with ongoing bisphosphonate therapy and fracture prevention strategies.

Q2.What is the success rate?

Intramedullary rodding reduces fracture frequency by 60-80% at Arthoscenter. Most children show improved mobility and quality of life.

Q3.What is the cost?

Cost varies by procedures needed, typically ₹2-5 lakhs per surgery. PMJAY/BSKY accepted. Bisphosphonate costs additional. Book ₹999 consultation.

Considering This Surgery?

Book an online video consultation with Dr. Gurudeo Kumar for just ₹999 and get all your questions answered